31st EASDec Annual Meeting, 28th – 30th October 2021, Odense, Denmark.
PRELIMINEARY (<- Click for PDF)
THURSDAY, 28TH OCTOBER 2021
| 12:30 | Registration and lunch |
| 13:30 | Satellite Symposium 1 |
| To be announced | |
| 14:30 | Satellite Symposium 2 |
| Novartis | |
| 15:30 | Highlights and future directions from the 5th conference of Screening for Diabetic Retinopathy in Europe (www.drscreening2005.org.uk) |
| Moderators: Professor Tunde Peto, Belfast, and Dr Caroline Styles, Dunfermline | |
| 16:00 | Break |
| 16:30 | Satellite Symposium 3 |
| Alimera Sciences | |
| 17:30 | Satellite Symposium 4 |
| Optos | |
| 18:30 | Official opening of EASDec |
| President of EASDec, Professor Rafael Simó, Barcelona | |
| Chair of Organizing Committee, Professor Jakob Grauslund, Odense | |
| 18:45 | Annual Meeting Welcome Reception (see Social Events for further information) |
| HC Andersens House, Hans Jensen Stræde 45 (100 meters from conference venue) | |
| 20:00 | End of the day |
FRIDAY, 29TH OCTOBER 2021
| 08:00 | Registration |
| 09:00 | Introduction and welcome |
| President of EASDec, Professor Rafael Simó, Barcelona | |
| Chair, Local Organizing Committee, Professor Jakob Grauslund, Odense | |
| 09:15 | Session 1: Experimental and translational research in diabetic eye complications |
| Chairs: Professor Reinier Schlingemann, Amsterdam, and Associate Professor Patrice Fort, Ann Arbor | |
| 09:16 | Topical ocular administration of sitagliptin, a DPP-4 inhibitor, prevents the downregulation of neuroretinal presynaptic proteins induced by diabetes (abstract 30) |
| Dr Cristina Hernandez, Barcelona | |
| 09:27 | Characterization of a new immortalized human microglial cell line and its pro-inflammatory activation (abstract 35) |
| Dr Aurora Mazzeo, Torino | |
| 09:38 | Towards a better understanding of PLVAP in vascular permeability: a proteomic approach to identify interacting partners of PLVAP (abstract 95) |
| Ms Esmeralda Bosma, Amsterdam | |
| 09:49 | Immunomodulation of microglia/macrophage interaction and its effect in diabetic retinopathy progression (abstract 55) |
| Ms Fatima Cano-Cano, Cadíz | |
| 10:00 | Mapping the daily rhythmic transcriptome in the diabetic retina (abstract 68) |
| Dr Eleni Beli, Belfast | |
| 10:11 | Winner of the EASDec Young Investigator Award in honour of Anne-Katrin Sjolie |
| Circadian clocks in diabetic retinal endothelial cells (abstract 70) | |
| Ms Hanagh Winter, Belfast | |
| 10:22 | Session conclusions by the moderators |
| 10:25 | Coffee break |
| 10:40 | Session 2: Epidemiology of ocular and systemic complications in diabetes |
| Chairs: Professor Ryo Kawasaki, Osaka, and Professor Morten Moe, Oslo | |
| 10:41 | Free-registration award-winning abstract for young scientist |
| Five-year incidence and progression of age-related macular degeneration in people with diabetes (abstract 80) | |
| Ms Dewi Romdhoniyyah, Liverpool | |
| 10:52 | Relationship between diabetic retinopathy and systemic neurodegenerative diseases: a systematic review and meta-analysis (abstract 16) |
| Professor Jakob Grauslund, Odense | |
| 11:03 | Non-attendance at diabetic eye screening in the Danish nationwide screening program (abstract 50) |
| Dr Anne Thykjær, Odense | |
| 11:14 | Association between diabetic retinopathy and glaucoma: results from a national screening program (abstract 41) |
| Dr Signe Sperling, Odense | |
| 11:25 | Prevalence and progression of diabetic retinopathy and macular edema during pregnancy in women with type 1 and type 2 diabetes (abstract 51) |
| Ms Nina Pappot, Copenhagen | |
| 11:36 | Do systematic diabetic retinopathy screening programmes prevent severe sight impairment? (abstract 91) |
| Dr Caroline Styles, Dunfermline | |
| 11:47 | Session conclusions by the moderators |
| 11:50 | Eva Kohner Lecture |
| Chair: Professor Tunde Peto, Belfast. | |
| Awardee: Professor Simon Harding, Liverpool. | |
| 12:35 | Lunch |
| 12:35-13:00: Poster presenters | |
| 13:00-13:30: All | |
| 13:00 | Session 3: Poster session |
| Poster formats will be 84 cm (wide) x 118 cm (height). Materials for mounting will be available at the venue. | |
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1 - Experimental research
Free-registration award-winning abstract for young scientist 1-01: Optimization of immunofluorescent detection of vascular markers on frozen human retinal sections (abstract 45) Ms Noëlle Bakker, Amsterdam
1-02: Correlation between the aqueous humor proteome and severity of diabetic macular edema (abstract 28) Dr Lasse Cehofski, Odense
1-03: On the possible role of damage of the endothelium of capillaries of retina after administration of diabetogenic zinc binding chemicals (abstract 21) Professor Gabit Meyramov, Karaganda
2 – Diabetic eye screening Moderator: Dr Deborah Broadbent, Liverpool
Free-registration award-winning abstract for young scientist 2-01: Identifying undetected prevalent disease: the first-pass effect in diabetic retinopathy screening programs (abstract 47) Dr Recivall Salongcay, Manila
Free-registration award-winning abstract for young scientist 2-02: Five year outcomes of diabetic eye screening in patients aged 80 years (abstract 40) Ms Nichola Albutt, Birmingham
2-03: A qualitative study on barriers and enablers to uptake of diabetic retinopathy screening by people with diabetes in the western province of Sri Lanka (abstract 83) Dr Mapa Piyasena, London
2-04: Inclusion of diabetic retinopathy screening strategies in national level diabetes care planning in low and middle-income countries: a scoping review (abstract 67) Dr Katie Curran, Belfast
2-05: Out of hours diabetic eye screening – a high risk group (abstract 72) Mr Richard Aldred, Gloucestershire
2-06: Diabetic retinopathy in pregnancy: screening attendance rates and development of disease (abstract 25) Ms Leanne Bird, Birmingham
Free-registration award-winning abstract for young scientist 2-07: Progression of diabetic retinopathy in type 1 and 2 diabetes during pregnancy and postpartum in the Danish national diabetes retinopathy screening program (abstract 89) Ms Janni Larsson, Roskilde
2-08: Treatment and follow up of patients graded as R3 (proliferative retinopathy) by diabetic retinopathy screening programme (DRSP) in Belfast, Northern Ireland (abstract 59) Dr Adele Heaney, Belfast
2-09: Diabetic retinopathy screening in individuals with severe mental illness (abstract 20) Mr John Sandford, Birmingham
2-10: Diabetic eye screening outcomes after non-attendance for three or more years (abstract 27) Ms Latesha Brown, Birmingham
2-11: Diabetes-related blindness between 1999 and 2018 in Denmark (abstract 92) Dr Søren Blindbæk, Odense
2-12: A retrospective analysis of factors affecting attendance at the Northern Ireland Diabetic Eye Screening Programme in young people with diabetes aged 12-26 (abstract 38) Ms Laura Cushley, Belfast
2-13: Impacts on eye health for patients who fail to attend hospital ophthalmology appointments (abstract 88) Ms Joanne Harmon, Cork
2-14: Updating a diabetic eye screening programme - a long and winding road (abstract 79) Ms Irene Stratton, Gloucester
3 - Epidemiology Moderator: Dr Karl-Johan Hellgren, Karlstad
3-01: Diabetic retinopathy and risk of prevalent and 5-year incident cardiovascular disorders in type 2 diabetes (abstract 37) Ms Lonny Stokholm, Odense
3-02: Characteristic features of diabetic retinopathy (DR) in UK BIOBANK (UKBB) (abstract 75) Dr Michaell Quinn
3-03: Characteristics of diabetic retinopathy in the Funen Diabetes Database based on latent class analysis (abstract 61) Dr Morten Larsen, Odense
3-04: Progression to proliferative diabetic retinopathy in the Danish Registry of Diabetic Retinopathy (abstract 64) Dr Sebastian Dinesen, Odense
3-05: Relationship between diabetic retinopathy and primary open-angle glaucoma in patients with diabetes mellitus (abstract 44) Ms Marianne Kjærsgaard, Odense
3-06: Inverse cross-sectional and longitudinal relations between diabetic retinopathy and obstructive sleep apnea in type 2 diabetes: results from a national screening program (abstract 13) Professor Jakob Grauslund, Odense
Free-registration award-winning abstract for young scientist 3-07: Incidence of acute angle closure glaucoma in the Northern Ireland Diabetic Eye Screening Programme (DESPNI) between 2016-2021 (abstract 102) Dr Matt O’Donell, Belfast
3-08: Diabetic retinopathy as a potential marker of protection of prevalent and incident migraine: results from a national cohort study (abstract 14) Dr Anna Vergmann, Odense
3-09: Diabetic retinopathy and chronic respiratory failure: a national register-based cohort study (abstract 34) Dr Benjamin Thinggaard, Odense
3-10: Diabetic retinopathy as a potential marker of Parkinson’s disease: results from a nationwide register-based cohort study (abstract 19) Ms Maria Larsen, Odense
3-11: Diabetic retinopathy and risk of major depression: bidirectional results from a Danish register-based nationwide cohort study (abstract 33) Dr Frederik Pedersen, Odense
4 - Clinical studies Moderator: Professor Toke Bek, Aarhus
4-01: Disorganisation of Retinal Inner Layers (DRIL) in participants with diabetic macular oedema: The RELIGHT Study (abstract 96) Ms Catherine Jamison, Belfast
4-02: Risk of progression of type 2 diabetes individuals with non-proliferative retinopathy: Characterization of phenotypes in a 1-year follow-up study (abstract 36) Dr Luisa Ribeiro, Coimbra
4-03: Comparison of mean HbA1c value and ΣexcessA1C index as predictors of retinopathy development at different diabetes duration (abstract 63) Dr Akira Hirose, Tokyo
4-05: Subjective visual disturbances in relation to fluctuating blood glucose levels in adult patients with diabetes mellitus: results from a pilot study (abstract 43) Mr Martin Rasmussen, Odense
4-06: Is visual function altered in people with uncomplicated type 2 diabetes or with early diabetic retinopathy? (abstract 71) Dr Karl-Johan Hellgren, Karlstad
Free-registration award-winning abstract for young scientist 4-07: Long-term visual outcomes and morphologic biomarkers of vision loss in eyes with diabetic macular edema treated with anti-VEGF therapy (abstract 106) Dr Enrico Borrelli, Milan
4-08: Dry eye symptoms and signs in patients with type 2 diabetes (abstract 97) Ms Siv Sandvik, Kongsberg
4-09: The statistician will see you now – how to make the best of a scarce resource (abstract 77) Ms Irene Straton, Gloucester
5 - Retinal imaging Moderator: Steve Aldington, Gloucestershire
5-01: The retinal oxygen saturation can be used to differentiate retinal neovascularisations from intraretinal microvascular abnormalities (IRMAs) in diabetic retinopathy (abstract 90) Dr Line Petersen, Aarhus
5-02: The importance of optical coherence tomography (OCT) for identification of clinically significant macular oedema (CSMO) in UK BIOBANK (UKBB) (abstract 78) Dr Barbra Hamill, Belfast
5-03: Comparison of different metrics for the identification of capillary closure in diabetic retinopathy using OCTA (abstract 57) Ms Inês Marques, Coimbra
5-04: Suspected diabetic retinopathy (DR) related changes in UK BIOBANK (UKBB) (abstract 103) Mr Alan Sproule, Belfast
5-05: Retinal vessel density, vessel diameter and oxygen saturation are associated with non-proliferative diabetic retinopathy in young patients with type 1 diabetes (abstract 65) Dr Nina Veiby, Oslo
5-06: Localization of retinal lesions in diabetic retinopathy in a virtual ocular learning platform (VIOLA) (abstract 73) Dr Malin Lundberg Rasmussen, Odense
5-07: Agreement between experts in the detection of diabetic retinopathy associated lesions in a virtual ocular learning platform (VIOLA) (abstract 18) Mr Martin Hubel, Odense
Free-registration award-winning abstract for young scientist 5-08: Optical coherence tomography (OCT) for diabetic maculopathy in a digital surveillance clinic (abstract 39) Ms Adele Farnsworth, Birmingham
6 - Automated screening Moderator: Associate Professor Malin Lundberg Rasmussen, Odense
6-01: Detection of diabetic retinopathy lesions using deep learning based semantic segmentation in retinal 45 degrees 6-field images (abstract 76) Mr Jakob Andersen, Odense
Free-registration award-winning abstract for young scientist 6-02: Testing the performance of risk prediction models to determine progression to referable diabetic retinopathy (RDR) in an Irish type 2 diabetes cohort (abstract 58) Dr John Smith, Belfast
6-03: Comparing SIVA and VAMPIRE for vascular geometric findings in patients with type 1 diabetes (abstract 26) Dr Sami Dabbah, Odense
6-04: CHIldren Living with Diabetes See and Thrive with AI Review: CHILDSTAR (abstract 86) Ms Noelle Whitestone, Belfast
6-05: Creating artificially training data for AI detection of retinal microaneurysms (abstract 81) Mr Simon Lyck Bjært Sørensen, Odense
6-06: Performance evaluation of software-assisted diabetic retinopathy screening (abstract 105) Mr Tobias Nissen, Aalborg
7 - Medical and surgical treatment of diabetic retinopathy Moderator: Professor Simon Harding, Liverpool
7-01: Pretraining on abstract modules on a virtual reality vitreoretinal simulator is a waste of time (abstract 56) Ms Sarah Bjørn Petersen, Odense
Free-registration award-winning abstract for young scientist 7-02: Vitrectomy for sight-threatening diabetic retinopathy in Denmark 1999-2019: a national, registry-based study (abstract 31) Dr Thomas Torp, Odense
7-03: Treating diabetic macular oedema: 12-weeks intervals in the first year (abstract 104) Professor Tunde Peto, Belfast
7-04: The impact of laboratory findings and optical coherence tomography biomarkers on response to intravitreal anti-VEGF treatment in patients with diabetic macular edema (abstract 108) Professor Irini Chatziralli, Athens
7-05: Functional and structural efficacy of a novel combinational therapy of aflibercept and timely focal/grid photocoagulation in diabetic macular edema: do clinical study results compare favorably with a standard-of-care treated real-life population? (abstract 32) Mr Mathias Jørgensen, Odense
7-06: Lipoproteins as biomarkers of diabetic retinopathy in type 1 diabetic patients (abstract 94) Dr Natalia Palarie, Chisinau
7-07: The effect of smoking on retinal nerve fiber layer and ganglion cell complex in patients with diabetes mellitus (abstract 54) Ms Kübra Özata Gündgdu, Serdivan
7-08: Assessment of complications during the late postoperative period for patients with diabetes mellitus after drainage surgery of secondary neovascular glaucoma (abstract 49) Ms Valeriya Biletskaya, Moscow |
| 15:00 | Keynote lecture 1: Translating epidemiological studies into clinical care in diabetes |
| Professor Ryo Kawasaki, Osaka | |
| 15:30 | Session 4: Clinical studies and novel treatments of diabetic retinopathy |
| Chairs: Dr Stela Vujosevic, Milan, and Professor Einar Stefánsson, Reykjavik | |
| 15:31 | The levels of placental growth factor and other proteins in the vitreous of patients undergoing diabetic vitrectomy and the effect of bevacizumab as compared to aflibercept pre-treatment (abstract 93) |
| Dr Ingeborg Klaassen, Amsterdam | |
| 15:42 | The risk for developing vision threatening retinopathy after cataract surgery in diabetic patients depends on the post-operative follow-up time (abstract 98) |
| Professor Toke Bek, Aarhus | |
| 15:53 | Are there still indications for macular laser in diabetic macular oedema? (abstract 48) |
| Ms Angela Dale, Gloucestershire | |
| 16:04 | Effect of calcium dobesilate in patients with subclinical diabetic macular edema: the CADODIAME study (abstract 23) |
| Dr Olga Simó-Servat, Barcelona | |
| 16:15 | Factors associated with the response to fluocinolone acetonide 0.19 mg in diabetic macular edema evaluated as the area-under-the-curve (abstract 15) |
| Dr Maria Vittoria Cicinelli, Milan | |
| 16.26 | Free-registration award-winning abstract for young scientist |
| Macular function and structure in early diabetic retinopathy (abstract 87) | |
| Dr Jae Yee Ku, Liverpool | |
| 16:37 | Session conclusions by the moderators |
| 16:40 | Break |
| 16:55 | Key note lecture 2: Diabetic eye screening: one size do not fit all |
| Professor Einar Stefánsson, Reykjavik | |
| 17:25 | Annual General Meeting |
| 18:00 | End of the day |
| 19:00 | Conference dinner (see Social Events for further information) |
| Restaurant Nordatlanten, Nordatlantisk promenade 1 | |
| We meet at conference venue at 19:00 for a 1.8km walk to restaurant |
SATURDAY, 30TH OCTOBER 2021
| 08:15 | Registration |
| 08:45 | Session 5: Providing ocular and systemic prevention and care in diabetes |
| Chairs: Professor Rafael Simó, Barcelona, and Professor Kurt Højlund, Odense | |
| 08:46 | Free-registration award-winning abstract for young scientist |
| Early worsening of retinopathy in people with diabetes after rapid improvement in glycaemic control: a systematic review (abstract 46) | |
| Dr Handan Akil, Liverpool | |
| 08:57 | MFAP4 immunotherapy-mediated inhibition of retinal neovascularization and vascular leakage (abstract 17) |
| Dr Anders Schlosser, Odense | |
| 09:08 | Diabetic retinopathy and skin tissue advanced glycation end products are biomarkers of vascular events in type 2 diabetic patients: results of the “PRECISED” study (abstract 22) |
| Ms Alejandra Planas, Barcelona | |
| 09:19 | Association of sight threatening diabetic retinopathy in type 1 diabetes with subclinical atherosclerosis disease burden – five year Indian study (abstract 53) |
| Dr Kiran Shah, Mumbai | |
| 09:30 | Session conclusions by the moderators |
| 09:33 | Mini Symposium: Diabetic retinopathy in relation to ocular and systemic disease: pearls and pitfalls from a Danish national registry-linkage study |
| Chair: Professor Jakob Grauslund, Odense | |
| Expert panel: Professor Kurt Højlund (the diabetologist), Professor Tunde Peto (the ophthalmologist), Professor Ryo Kawasaki (the ophthalmo-epidemiologist) | |
| 09:34 | The Ocular And Systemic complications In diabetic retinopathy Study (OASIS): study design and methodology |
| Professor Jakob Grauslund, Odense | |
| 09:42 | Rapid fire presentation 1: DR as a marker of neurodegenerative disease |
| Dr Frederik Nørregaard Pedersen, Odense | |
| 09:48 | Rapid fire presentation 2: DR as a marker of cardiovascular disease |
| Ms Lonny Stokholm, Odense | |
| 09:54 | Rapid fire presentation 3: DR as a marker of ocular disease |
| Dr Sebastian Dinesen, Odense | |
| 10:00 | Panel discussion: what can be learned from big data, register-linking studies? |
| 10:10 | Keynote Lecture 3: A journey through multi-omics analyses of diabetic retinopathy |
| Associate Professor Patrice Fort, Ann Arbor | |
| 10:55 | Coffee Break |
| 11:15 | Session 6: Novel methods in retinal imaging |
| Chairs: Professor Tunde Peto, Belfast, and Professor Jakob Grauslund, Odense | |
| 11:16 | OCTA metrics monitor severity progression of diabetic retinopathy (abstract 29) |
| Professor José Cunha-Vaz, Coimbra | |
| 11:27 | Ganglion cell-inner plexiform layer alteration in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study (abstract 42) |
| Ms Maria Madeira, Coimbra | |
| 11:38 | Microaneurysm Turnover in eyes with mild nonproliferative diabetic retinopathy is associated with progression and development of sight-threatening complications: a 5-year longitudinal study (abstract 100) |
| Dr Ana Rita Santos, Coimbra | |
| 11:49 | Three-year OCT-angiography evaluation in patients with diabetes mellitus type 1 and 2 without clinical signs of diabetic retinopathy and with good glycemic control (abstract 62) |
| Dr Stela Vujosevic, Milan | |
| 12:00 | Session conclusions by the moderators |
| 12:03 | Session 7: Entering the era of artificial intelligence in diabetic eye screening |
| Chairs: Professor Frank Verbraak, Amsterdam, and Professor Rajeeth Savarimuthu, Odense | |
| 12:04 | Development of an artificial intelligence-based diabetic retinopathy screening tool for OPTOS ultra-widefield imaging (abstract 107) |
| Professor Tunde Peto, Belfast | |
| 12:15 | Trustworthy AI: closing the gap between development and integration of AI in Ophthalmology (abstract 66) |
| Ms Cristina González-Gonzalo, Amsterdam | |
| 12:26 | Accuracy of a diabetic retinopathy grading algorithm used with a hand-held fundus camera in Southern Malawi (abstract 99) |
| Dr Joe Aslan, Zomba | |
| 12:37 | Testing of thirteen artificial intelligence algorithms for diabetic retinopathy using fundus images from Finland (abstract 69) |
| Dr Petri Huhtinen, Oulo | |
| 12:48 | Session conclusions by the moderators |
| 12:51 | Best poster prize ceremony and closing remarks |
| President of EASDec, Professor Rafael Simó, Barcelona | |
| 13:00 | Conference close and lunch to go |